菜单 基因医生

烟酸(na;烟酸)通过烟酸磷酸核糖基转移酶(naprt;ec 2.4.2.11)转化为na单核苷酸(namn),然后转化为na腺嘌呤二核苷酸(naad),最后转化为nicotinamide腺嘌呤二核苷酸(nad),在细胞氧化还原反应中起到辅酶的作用,是多种O型化合物的重要组成部分。f细胞代谢过程,包括应激反应(Hara等人,2007年)。
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).

基因名:NAPRT
别名:NAPRT1,PP3856
基因ID:93100
Chromosome:
(GRCh37)
8 Start: 144656955 End: 144660819 Strand: -1
信号通路:  
靶向药: GNE-617 
化疗药:
NAPRT 基因突变与药物