菜单 基因医生

这个位点编码一个富含蛋白质的dna相互作用域。编码蛋白是swi/snf染色质重塑复合物的组成部分,可能在细胞周期激活中起作用。该基因座编码的蛋白质类似于含有1a蛋白的at-rich相互作用域,这两种蛋白作为swi/snf复合物的替代、互斥和亚基发挥作用。相关的复合物起着相反的作用。选择性剪接导致多个转录变体。[由RefSeq提供,2016年10月]
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

基因名:ARID1B
别名:CSS1,OSA2,6A3-5,DAN15,MRD12,P250R,BRIGHT,BAF250B,ELD/OSA1
基因ID:57492
Chromosome:
(GRCh37)
6 Start: 157098980 End: 157531913 Strand: 
信号通路: 基因组不稳定 
ARID1B 基因突变与药物