菜单 基因医生

该基因编码的蛋白质是recq-deah螺旋酶家族的成员,与乳腺癌1型(brca1)的brct重复序列相互作用。结合复合体在1型乳腺癌(brca1)正常双链断裂修复功能中起重要作用。这个基因可能是生殖系癌症诱发突变的靶点。[由RefSeq提供,2008年7月]
The protein encoded by this gene is a member of the RecQ DEAH helicase family and interacts with the BRCT repeats of breast cancer, type 1 (BRCA1). The bound complex is important in the normal double-strand break repair function of breast cancer, type 1 (BRCA1). This gene may be a target of germline cancer-inducing mutations. [provided by RefSeq, Jul 2008]

基因名:BRIP1
别名:OF,BACH1,FANCJ
基因ID:83990
Chromosome:
(GRCh37)
17 Start: 59756547 End: 59940920 Strand: 
信号通路: 基因组不稳定  遗传相关 
BRIP1 基因突变与药物